Committee on the Use of Human Subjects (CUHSR/IRB)

You can take this quiz as many times as necessary, however, a score of 75% is required to be certified to submit an application to the Missouri Western CUHSR (IRB). The system will keep track of the number of attempts. The information needed to pass this quiz is available in the links listed in the "Certification Process" portion of the Missouri Western CUHSR web page.
EMail Address: (must be the same address you will use to submit proposals)
Your Full Name:
1. According to the Federal Government which of the following does NOT constitute research involving human participants?
A study of tissue samples linked to someone's medical records
A study using observations of public behavior at the mall
An anonymous survey given to students enrolled in BIO101
A study using sensitive information collected through a survey voluntarily completed by study participants, in which the survey was coded so respondents could be matched to the mailing list for follow-up.
2. Three basic ethical principles which became the standard for the acceptable conduct of research involving human subjects in the United States, "Respect for Persons", "Justice" and "Beneficence" are the guiding principles behind the IRB process. In which of the following were these principles first outlined?
The Nuremburg Trial
The Tuskeegee Study
The "Common Rule"
The Belmont Report
3. "Expedited Review" may be applied to research when
the Principal Investigator has certified it as expeditable.
it presents no more than minimal risk and involves only those procedures outlined in the federal regulations.
IRB approval is needed as quickly as possible.
the research is being conducted as a class requirement
4. Which of the following is NOT a criteria that the IRB uses to evaluate research proposals?
The design of the study is consistent with sound scientific principles, ethical guidelines, and legal requirements.
Risks to subjects are minimized using procedures consistent with sound research design and that do not unnecessarily expose subjects to risk.
Informed Consent is obtained when required, and additional appropriate safeguards have been provided if potentially vulnerable subjects are to be studied (e.g., children, prisoners,).
The political and community reaction to the research topic being studied.
5. When can research activities (data collection) begin?
As soon as the researcher is ready.
As soon as a proposal is submitted.
Two weeks after the committee meets
Only after you have received written (email) approval from the chair of the IRB
6. Which of the following requires written notification of the IRB?
Modifications to the research design
Extensions of time required to collect data
Adverse events
All of the above require notification of the IRB
7. Who is required to submit a final status report?
Just faculty and staff
Just students
Everyone
Only researchers who have changed their study since the proposal was submitted
8. How long will it take to get approval from the IRB?
Always less than 7 days
Less than 7 days if exempt or expedited review, after the monthly meeting if full review is required
After the monthly meeting
Immediately if you have special circumstances and need to collect data right away
9. Who has the primary responsibility for ensuring that the study has been approved by the IRB?
Federal Agencies
Funding Agencies
Principal Investigator
Research Team
10. All of the following are true of an IRB except:
It should have at least five members
At least three members should have an advanced degree in the scientific field related to the study
No members should have a vested interest in the research study under review
Members should be from diverse backgrounds regarding race, gender, and cultural heritage, and at least one member should not be associated with the institution
11. All of the following populations have additional and specific federal regulations be met for their protection except?:
Prisoners
Children
Fetuses
The elderly
12. ______________________ highlighted the vulnerability of institutionalized children as participants in research and concerned the issue of children deliberately infected with the hepatitis virus.
Declaration of Helsinki
Nuremberg Code
Willowbrook Study
Belmont Report
13. The Belmont principle that is applied when attempting to distribute research risks fairly and without bias is:
Beneficence
Justice
Respect for Persons
Equality
14. Which of the following is not one of the required sections of a project summary
Confidentiality
Research Methodology
Literature Review
Research Risks And Benefits
15. MWSU informed consent forms (when required) must list all the following except:
A description of foreseeable risks to the participants
A statement describing all the organizations or agencies funding the research study
A statement of describing to what extent records will be kept confidential
A statement that participation is voluntary and participants may refuse to participate or withdraw at any time
16. At Missouri Western, informed consent is required ______________
Never
For any study that is not classfied as exempt
For non minimal risk studies, or studies where the IRB has requested informed consent
For all projects involving human subjects, except under the specific circumstances outlined in the Common Rule (46.116.f.3 and 46.117.c)
17. Who has the responsibility for initially reporting specified adverse events?
The IRB
The data and safety monitoring board
The FDA
The investigator and research team
18. The Declaration of Helsinki was a landmark international agreement on the treatment of human subjects adopted by:
The U.S. Public Health Service
The United Nations
The World Medical Association
The U.S. Food and Drug Administration
19. A ____-tiered system of monitoring is required for the use of human subjects in research.
1
2
3
4
20. An IRB does not primarily function to:
Approve, request modifications or disapprove any research involving human subjects.
Insure that proper procedures and documentation of informed consent have been established by a researcher.
Judge the foreseeable risks and benefits to human subjects within a research project.
Judge the scientific validity of the research methodology employed in a project.
[ IRB HOMEPAGE ]

Any questions about proposals, procedures, etc. should be directed to the chair of the CUHSR